Synthetic versus tissue-engineered implants for joint replacement
نویسندگان
چکیده
منابع مشابه
Stem Cell‐Based Tissue‐Engineered Laryngeal Replacement
: Patients with laryngeal disorders may have severe morbidity relating to swallowing, vocalization, and respiratory function, for which conventional therapies are suboptimal. A tissue-engineered approach would aim to restore the vocal folds and maintain respiratory function while limiting the extent of scarring in the regenerated tissue. Under Good Laboratory Practice conditions, we decellulari...
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It is well accepted that the loss of meniscal function due to surgical removal is a significant factor in the onset of degenerative osteoarthritis of the knee. Few viable alternatives exist for the replacement of significantly damaged tissue. In this study, two potential designs for meniscus scaffolds were compared with a focus on the mechanical protection they provide the articular surfaces an...
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AIM A tissue-engineered periodontal ligament (PDL) around implants would represent an important new therapeutic tool to replace lost teeth. The PDL is the key to tooth anchoring; it connects tooth root and alveolar bone, and it sustains bone formation. MATERIALS AND METHODS Cells were isolated from PDL and cultured in a bioreactor on titanium pins. After the formation of multiple cellular lay...
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Tissue engineering has provided an alternative to traditional strategies to repair and regenerate temporomandibular joints (TMJ). A successful strategy to engineer osteochondral tissue, such as that found in the TMJ, will produce tissue that is both biologically and mechanically functional. Image-based design (IBD) and solid free-form (SFF) fabrication can be used to generate scaffolds that are...
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Molecular biomaterial engineering permits in vivo transplantation of cells and tissues, offering the promise of restoration of physiologic control rather than pharmacologic dosing with isolated compounds. We engrafted endothelial cells on Gelfoam biopolymeric matrices with retention of viability, normal growth kinetics, immunoreactivity, and biochemical activity. The production of heparan sulfa...
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ژورنال
عنوان ژورنال: Applied Bionics and Biomechanics
سال: 2008
ISSN: 1176-2322,1754-2103
DOI: 10.1080/11762320701816966